TPM1 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: TPM1
Target Synonym: AA986836;AI854628;Alpha tropomyosin;alpha-TM;Alpha-tropomyosin;C15orf13;cardiomyopathy;hypertrophic 3;CMD1Y;CMH3;HTM alpha;HTM-alpha;OTTHUMP00000163688;sarcomeric tropomyosin kappa;TM2;Tmpa;TMSA;Tpm-1;TPM1;TPM1;tropomyosin 1 (alpha);tropomyosin 1 (alpha) isoform 1;tropomyosin 1 (alpha) isoform 2;tropomyosin 1 (alpha) isoform 3;tropomyosin 1 (alpha) isoform 4;tropomyosin 1 (alpha) isoform 5;tropomyosin 1 (alpha) isoform 6;tropomyosin 1 (alpha) isoform 7;Tropomyosin 1;Tropomyosin alpha 1 chain;Tropomyosin alpha-1 chain;Tropomyosin;skeletal muscle alpha;Tropomyosin-1
Research Areas: Cancer;Cardiovascular;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P09493
Accession:
Background: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Concentration: 0.2 mg/mL
Immunogen: Recombinant protein of human TPM1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: WB 1:1000-1:5000;IHC 1:50-1:200
Calculated MW: 33kDa
ObservedMW:
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TPM1 Polyclonal Antibody
TPM1 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: TPM1
Target Synonym: AA986836;AI854628;Alpha tropomyosin;alpha-TM;Alpha-tropomyosin;C15orf13;cardiomyopathy;hypertrophic 3;CMD1Y;CMH3;HTM alpha;HTM-alpha;OTTHUMP00000163688;sarcomeric tropomyosin kappa;TM2;Tmpa;TMSA;Tpm-1;TPM1;TPM1;tropomyosin 1 (alpha);tropomyosin 1 (alpha) isoform 1;tropomyosin 1 (alpha) isoform 2;tropomyosin 1 (alpha) isoform 3;tropomyosin 1 (alpha) isoform 4;tropomyosin 1 (alpha) isoform 5;tropomyosin 1 (alpha) isoform 6;tropomyosin 1 (alpha) isoform 7;Tropomyosin 1;Tropomyosin alpha 1 chain;Tropomyosin alpha-1 chain;Tropomyosin;skeletal muscle alpha;Tropomyosin-1
Research Areas: Cancer;Cardiovascular;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P09493
Accession:
Background: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Concentration: 0.2 mg/mL
Immunogen: Recombinant protein of human TPM1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: WB 1:1000-1:5000;IHC 1:50-1:200
Calculated MW: 33kDa
ObservedMW:
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Description
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: TPM1
Target Synonym: AA986836;AI854628;Alpha tropomyosin;alpha-TM;Alpha-tropomyosin;C15orf13;cardiomyopathy;hypertrophic 3;CMD1Y;CMH3;HTM alpha;HTM-alpha;OTTHUMP00000163688;sarcomeric tropomyosin kappa;TM2;Tmpa;TMSA;Tpm-1;TPM1;TPM1;tropomyosin 1 (alpha);tropomyosin 1 (alpha) isoform 1;tropomyosin 1 (alpha) isoform 2;tropomyosin 1 (alpha) isoform 3;tropomyosin 1 (alpha) isoform 4;tropomyosin 1 (alpha) isoform 5;tropomyosin 1 (alpha) isoform 6;tropomyosin 1 (alpha) isoform 7;Tropomyosin 1;Tropomyosin alpha 1 chain;Tropomyosin alpha-1 chain;Tropomyosin;skeletal muscle alpha;Tropomyosin-1
Research Areas: Cancer;Cardiovascular;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P09493
Accession:
Background: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Concentration: 0.2 mg/mL
Immunogen: Recombinant protein of human TPM1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: WB 1:1000-1:5000;IHC 1:50-1:200
Calculated MW: 33kDa
ObservedMW:
