SQSTM1 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: SQSTM1
Target Synonym: A170;DMRV;EBI 3 associated protein of 60 kDa;EBI 3 associated protein p60;EBI3 associated protein of 60 kDa;EBI3 associated protein p60;EBI3-associated protein of 60 kDa;EBIAP;FTDALS3;MGC127197;ORCA;OSF-6;Osi;OSIL;Oxidative stress induced like;p60;p62;p62B;Paget disease of bone 3;PDB 3;PDB3;Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa;Phosphotyrosine independent ligand for the Lck SH2 domain p62;Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa;PKC-zeta-interacting protein;Protein kinase C-zeta-interacting protein;Sequestosome 1;Sequestosome-1;SQSTM 1;SQSTM;Sqstm1;STAP;STONE14;Ubiquitin binding protein p62;Ubiquitin-binding protein p62;ZIP 3;ZIP;ZIP3
Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q13501
Accession:
Background: Sequestosome 1 (SQSTM1/p62) is a multifunctional adaptor protein implicated in selective autophagy,cell signaling pathways,and tumorigenesis. p62 has been implicated in shuttling ubiquitinated and sometimes aggregated proteins for autophagic degradation. As a autophagy-specific substrate,p62 is degraded during the autophagic process,which makes intracellular level of p62 as a marker for autophagy flux. p62 is at the cross-roads of several signaling pathways including Ras/ Raf/ MAPK and NFκB and plays important role in cancer. p62 is a component of inclusion bodies/ protein aggregates found in human diseases,including Huntington's disease,Alzheimer's disease,Parkinson's disease in the brain,and nephropathic cystinosis in kidney (22074114,22860231,22714671). The molecular weight of p62 is predicted as 48/ 38 kDa,while western blot analyses using this antibody demonstrate the major band around 60-62 kDa in various tissues.
Concentration: 1.14 mg/mL
Immunogen: Synthetic peptide of human SQSTM1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Dilution: WB 1:500-1:2000;IHC 1:50-1:100
Calculated MW: 48 kDa
ObservedMW: Refer to figures
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SQSTM1 Polyclonal Antibody
SQSTM1 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: SQSTM1
Target Synonym: A170;DMRV;EBI 3 associated protein of 60 kDa;EBI 3 associated protein p60;EBI3 associated protein of 60 kDa;EBI3 associated protein p60;EBI3-associated protein of 60 kDa;EBIAP;FTDALS3;MGC127197;ORCA;OSF-6;Osi;OSIL;Oxidative stress induced like;p60;p62;p62B;Paget disease of bone 3;PDB 3;PDB3;Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa;Phosphotyrosine independent ligand for the Lck SH2 domain p62;Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa;PKC-zeta-interacting protein;Protein kinase C-zeta-interacting protein;Sequestosome 1;Sequestosome-1;SQSTM 1;SQSTM;Sqstm1;STAP;STONE14;Ubiquitin binding protein p62;Ubiquitin-binding protein p62;ZIP 3;ZIP;ZIP3
Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q13501
Accession:
Background: Sequestosome 1 (SQSTM1/p62) is a multifunctional adaptor protein implicated in selective autophagy,cell signaling pathways,and tumorigenesis. p62 has been implicated in shuttling ubiquitinated and sometimes aggregated proteins for autophagic degradation. As a autophagy-specific substrate,p62 is degraded during the autophagic process,which makes intracellular level of p62 as a marker for autophagy flux. p62 is at the cross-roads of several signaling pathways including Ras/ Raf/ MAPK and NFκB and plays important role in cancer. p62 is a component of inclusion bodies/ protein aggregates found in human diseases,including Huntington's disease,Alzheimer's disease,Parkinson's disease in the brain,and nephropathic cystinosis in kidney (22074114,22860231,22714671). The molecular weight of p62 is predicted as 48/ 38 kDa,while western blot analyses using this antibody demonstrate the major band around 60-62 kDa in various tissues.
Concentration: 1.14 mg/mL
Immunogen: Synthetic peptide of human SQSTM1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Dilution: WB 1:500-1:2000;IHC 1:50-1:100
Calculated MW: 48 kDa
ObservedMW: Refer to figures
Original: $62,461.47
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$18,738.44Product Information
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Description
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: SQSTM1
Target Synonym: A170;DMRV;EBI 3 associated protein of 60 kDa;EBI 3 associated protein p60;EBI3 associated protein of 60 kDa;EBI3 associated protein p60;EBI3-associated protein of 60 kDa;EBIAP;FTDALS3;MGC127197;ORCA;OSF-6;Osi;OSIL;Oxidative stress induced like;p60;p62;p62B;Paget disease of bone 3;PDB 3;PDB3;Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa;Phosphotyrosine independent ligand for the Lck SH2 domain p62;Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa;PKC-zeta-interacting protein;Protein kinase C-zeta-interacting protein;Sequestosome 1;Sequestosome-1;SQSTM 1;SQSTM;Sqstm1;STAP;STONE14;Ubiquitin binding protein p62;Ubiquitin-binding protein p62;ZIP 3;ZIP;ZIP3
Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q13501
Accession:
Background: Sequestosome 1 (SQSTM1/p62) is a multifunctional adaptor protein implicated in selective autophagy,cell signaling pathways,and tumorigenesis. p62 has been implicated in shuttling ubiquitinated and sometimes aggregated proteins for autophagic degradation. As a autophagy-specific substrate,p62 is degraded during the autophagic process,which makes intracellular level of p62 as a marker for autophagy flux. p62 is at the cross-roads of several signaling pathways including Ras/ Raf/ MAPK and NFκB and plays important role in cancer. p62 is a component of inclusion bodies/ protein aggregates found in human diseases,including Huntington's disease,Alzheimer's disease,Parkinson's disease in the brain,and nephropathic cystinosis in kidney (22074114,22860231,22714671). The molecular weight of p62 is predicted as 48/ 38 kDa,while western blot analyses using this antibody demonstrate the major band around 60-62 kDa in various tissues.
Concentration: 1.14 mg/mL
Immunogen: Synthetic peptide of human SQSTM1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Dilution: WB 1:500-1:2000;IHC 1:50-1:100
Calculated MW: 48 kDa
ObservedMW: Refer to figures
