Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SOCS1

Target Synonym: CISH 1;CISH1;Cytokine inducible SH2 protein 1;JAB;JAK binding protein;JAK-binding protein;Janus kinase binding protein;SOCS 1;SOCS-1;Socs1;SOCS1;SSI 1;SSI-1;SSI1;STAT induced STAT inhibitor 1;STAT-induced STAT inhibitor 1;Suppressor of cytokine signaling 1;Supressor of cytokine signalling 1;TEC interacting protein 3;Tec-interacting protein 3;TIP 3;TIP-3;TIP3

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O15524

Accession:

Background: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human SOCS1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300

Calculated MW: 24kDa

ObservedMW: