Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SETD2

Target Synonym: EC 2.1.1.43;FLJ16420;FLJ22472;FLJ23184;FLJ45883;HBP231;HIF 1;HIF-1;HIF1;HIP-1;Histone lysine N methyltransferase SETD2;Histone-lysine N-methyltransferase SETD2;hSET2;HSPC069;Huntingtin interacting protein 1;Huntingtin interacting protein;Huntingtin interacting protein B;Huntingtin interacting protein HYPB;Huntingtin yeast partner B;Huntingtin-binding protein;231-KD;Huntingtin-interacting protein 1;Huntingtin-interacting protein B;HYPB;KIAA1732;KMT3A;Lysine N methyltransferase 3A;Lysine N-methyltransferase 3A;p231HBP;SET domain containing 2;SET domain-containing protein 2;SET2;SETD2;SETD2

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9BYW2

Accession:

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Concentration: 0.2 mg/mL

Immunogen: Recombinant protein of human SETD2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: