Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/13A

Target Synonym: brain sodium channel type I;EIEE6;FEB3;FEB3A;FHM3;GEFS+2;GEFSP2;HBSC I;HBSCI;NAC1;Nav 1.1;RBI;SCN1;Scn1a;SCN1A;SMEI;Sodium channel protein brain I alpha subunit;Sodium channel protein brain I subunit alpha;Sodium channel protein type 1 subunit alpha;Sodium channel protein type I subunit alpha;Sodium channel voltage gated type 1 alpha subunit;Sodium channel voltage gated type I alpha polypeptide;Voltage-gated sodium channel subunit alpha Nav1.1

Research Areas: Cancer;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P35498

Accession:

Background: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Concentration: 0.5 mg/mL

Immunogen: Synthetic peptide of human SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/13A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: