Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: RRM1

Target Synonym: R1;Ribonucleoside diphosphate reductase large subunit;Ribonucleoside diphosphate reductase M1 chain;Ribonucleoside diphosphate reductase subunit M1;Ribonucleoside reductase;large subunit;Ribonucleoside-diphosphate reductase large subunit;Ribonucleoside-diphosphate reductase subunit M1;Ribonucleotide reductase large chain;Ribonucleotide reductase large subunit;Ribonucleotide reductase M1;Ribonucleotide reductase M1 polypeptide;Ribonucleotide reductase R1 subunit;Ribonucleotide reductase;M1 subunit;RIR 1;RIR1;RIR1;RR 1;RR1;RRM 1;RRM1

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P23921

Accession:

Background: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human RRM1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 90kDa

ObservedMW: