Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: RNASE1

Target Synonym: HP-RNase;Pancreatic ribonuclease;Rib 1;RIB-1;Rib1;Ribonuclease 1;Ribonuclease A;Ribonuclease a family 1;Ribonuclease pancreatic;Ribonuclease RNase A family 1;Ribonuclease RNase A family 1 pancreatic;RNAS1_HUMAN;RNase 1;RNase A;RNase UpI-1;Rnase1;RNAseA

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P07998

Accession:

Background: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Concentration: 0.9 mg/mL

Immunogen: Fusion protein of human RNASE1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:100

Calculated MW: 18 kDa

ObservedMW: Refer to figures