RHOA Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: RHOA
Target Synonym: Aplysia ras related homolog 12;ARH12;ARHA;H 12;H12;Oncogene RHO H12;Ras homolog family member A;Ras homolog gene family member A;Rho A;Rho cDNA clone 12;RHO H12;RHO12;RHOA;RHOA;RHOH12;Small GTP binding protein Rho A;Transforming protein Rho A;Transforming protein RhoA
Research Areas: Cancer;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P61586
Accession:
Background: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Concentration: 0.2 mg/mL
Immunogen: Synthetic peptide of human RHOA
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 22kDa
ObservedMW:
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RHOA Polyclonal Antibody
RHOA Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: RHOA
Target Synonym: Aplysia ras related homolog 12;ARH12;ARHA;H 12;H12;Oncogene RHO H12;Ras homolog family member A;Ras homolog gene family member A;Rho A;Rho cDNA clone 12;RHO H12;RHO12;RHOA;RHOA;RHOH12;Small GTP binding protein Rho A;Transforming protein Rho A;Transforming protein RhoA
Research Areas: Cancer;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P61586
Accession:
Background: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Concentration: 0.2 mg/mL
Immunogen: Synthetic peptide of human RHOA
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 22kDa
ObservedMW:
Original: $358.65
-70%$358.65
$107.59Product Information
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Description
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: RHOA
Target Synonym: Aplysia ras related homolog 12;ARH12;ARHA;H 12;H12;Oncogene RHO H12;Ras homolog family member A;Ras homolog gene family member A;Rho A;Rho cDNA clone 12;RHO H12;RHO12;RHOA;RHOA;RHOH12;Small GTP binding protein Rho A;Transforming protein Rho A;Transforming protein RhoA
Research Areas: Cancer;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P61586
Accession:
Background: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Concentration: 0.2 mg/mL
Immunogen: Synthetic peptide of human RHOA
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 22kDa
ObservedMW:
