Recombinant Mouse IL-28B protein(His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: IL-28B
Target Synonym: Cytokine Zcyto;IL-12 subunit p;ZCYTO;Cytokine Zcyto22;Cytotoxic Lymphocyte Maturation Factor 35 kDa;IFNL4;IFN-Lambda-3;IFN-Lambda-4;IL-12 subunit p35;IL-12A;IL-28B;IL28C;IL-28C;Interferon Lambda-3;Interferon Lambda-4;Interleukin-12 subunit alpha;Interleukin-28B;Interleukin-28C;ZCYTO22;Il28;Il28b;Ifnl3
Research Areas:
Conjugation:
Target Species: Mouse
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: Q8CGK6
Accession: Q8CGK6
Background: Interleukin-28B; also known as Cytokine Zcyto22; Interferon lambda-3; Interferon lambda-4; IFNL3; IFNL4; ZCYTO22 and IL28B; is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition; IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Concentration:
Activity: Measure by its ability to protect HepG2 cells infected with encephalomyocarditis (EMC) virus.The ED50 for this effect is <20 ng/mL.
Sequence: Asp 20-Val 193
Purity: > 98 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 20.6 kDa
ObservedMW: 17-25 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Mouse IL-28B protein(His Tag)
Recombinant Mouse IL-28B protein(His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: IL-28B
Target Synonym: Cytokine Zcyto;IL-12 subunit p;ZCYTO;Cytokine Zcyto22;Cytotoxic Lymphocyte Maturation Factor 35 kDa;IFNL4;IFN-Lambda-3;IFN-Lambda-4;IL-12 subunit p35;IL-12A;IL-28B;IL28C;IL-28C;Interferon Lambda-3;Interferon Lambda-4;Interleukin-12 subunit alpha;Interleukin-28B;Interleukin-28C;ZCYTO22;Il28;Il28b;Ifnl3
Research Areas:
Conjugation:
Target Species: Mouse
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: Q8CGK6
Accession: Q8CGK6
Background: Interleukin-28B; also known as Cytokine Zcyto22; Interferon lambda-3; Interferon lambda-4; IFNL3; IFNL4; ZCYTO22 and IL28B; is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition; IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Concentration:
Activity: Measure by its ability to protect HepG2 cells infected with encephalomyocarditis (EMC) virus.The ED50 for this effect is <20 ng/mL.
Sequence: Asp 20-Val 193
Purity: > 98 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 20.6 kDa
ObservedMW: 17-25 kDa
Original: $9,128,649.38
-70%$9,128,649.38
$2,738,594.81Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: IL-28B
Target Synonym: Cytokine Zcyto;IL-12 subunit p;ZCYTO;Cytokine Zcyto22;Cytotoxic Lymphocyte Maturation Factor 35 kDa;IFNL4;IFN-Lambda-3;IFN-Lambda-4;IL-12 subunit p35;IL-12A;IL-28B;IL28C;IL-28C;Interferon Lambda-3;Interferon Lambda-4;Interleukin-12 subunit alpha;Interleukin-28B;Interleukin-28C;ZCYTO22;Il28;Il28b;Ifnl3
Research Areas:
Conjugation:
Target Species: Mouse
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: Q8CGK6
Accession: Q8CGK6
Background: Interleukin-28B; also known as Cytokine Zcyto22; Interferon lambda-3; Interferon lambda-4; IFNL3; IFNL4; ZCYTO22 and IL28B; is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition; IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Concentration:
Activity: Measure by its ability to protect HepG2 cells infected with encephalomyocarditis (EMC) virus.The ED50 for this effect is <20 ng/mL.
Sequence: Asp 20-Val 193
Purity: > 98 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 20.6 kDa
ObservedMW: 17-25 kDa
