Recombinant Mouse CD32b/FCGR2B Protein (His Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: CD32b;FCGR2B
Target Synonym: CD32;Fc gamma receptor IIB;Fc-gamma RII;Fc-gamma-RIIB;FcRII;Fcgr2;Fcgr2b;IgG Fc receptor II beta;Low affinity immunoglobulin gamma Fc region receptor II;Ly-17;Lymphocyte antigen 17
Research Areas:
Conjugation:
Target Species: Mouse
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: P08101
Accession: P08101
Background: Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.
Concentration:
Activity: Not validated for activity
Sequence: Thr30-Pro210
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 21.6 kDa
ObservedMW: 33 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Mouse CD32b/FCGR2B Protein (His Tag)
Recombinant Mouse CD32b/FCGR2B Protein (His Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: CD32b;FCGR2B
Target Synonym: CD32;Fc gamma receptor IIB;Fc-gamma RII;Fc-gamma-RIIB;FcRII;Fcgr2;Fcgr2b;IgG Fc receptor II beta;Low affinity immunoglobulin gamma Fc region receptor II;Ly-17;Lymphocyte antigen 17
Research Areas:
Conjugation:
Target Species: Mouse
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: P08101
Accession: P08101
Background: Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.
Concentration:
Activity: Not validated for activity
Sequence: Thr30-Pro210
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 21.6 kDa
ObservedMW: 33 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: CD32b;FCGR2B
Target Synonym: CD32;Fc gamma receptor IIB;Fc-gamma RII;Fc-gamma-RIIB;FcRII;Fcgr2;Fcgr2b;IgG Fc receptor II beta;Low affinity immunoglobulin gamma Fc region receptor II;Ly-17;Lymphocyte antigen 17
Research Areas:
Conjugation:
Target Species: Mouse
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: P08101
Accession: P08101
Background: Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.
Concentration:
Activity: Not validated for activity
Sequence: Thr30-Pro210
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 21.6 kDa
ObservedMW: 33 kDa
