Recombinant Human VEGF Receptor 2/VEGF R2/FLK-1/KDR (C-6His-Avi) Biotinylated
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: VEGF R2;FLK-1;KDR
Target Synonym: FLK-1;Fetal liver kinase 1;KDR;Kinase insert domain receptor;Protein-tyrosine kinase receptor flk-1;VEGF R2;VEGFR-2;VEGFR2;Vascular endothelial growth factor receptor 2
Research Areas: Signal Transduction;Microbiology;Cardiovascular;Cancer;metabolism;Stem cells
Conjugation: Biotinylated
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His-Avi
UNIProt ID: P35968
Accession: P35968
Background: Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. It also plays an essential role in promoting proliferation, survival, migration and differentiation of endothelial cells, reorganization of the actin cytoskeleton. VEGFR2 is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo.The adaptor protein SHB has been shown to interact with VEGFR2 in receptor tyrosine kinase signaling. In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
Concentration:
Activity: Not validated for activity
Sequence: Ala20-Glu764
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 86.1 kDa
ObservedMW: 120-150 kDa
Product Information
Product Information
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Shipping & Returns
Recombinant Human VEGF Receptor 2/VEGF R2/FLK-1/KDR (C-6His-Avi) Biotinylated
Recombinant Human VEGF Receptor 2/VEGF R2/FLK-1/KDR (C-6His-Avi) Biotinylated
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: VEGF R2;FLK-1;KDR
Target Synonym: FLK-1;Fetal liver kinase 1;KDR;Kinase insert domain receptor;Protein-tyrosine kinase receptor flk-1;VEGF R2;VEGFR-2;VEGFR2;Vascular endothelial growth factor receptor 2
Research Areas: Signal Transduction;Microbiology;Cardiovascular;Cancer;metabolism;Stem cells
Conjugation: Biotinylated
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His-Avi
UNIProt ID: P35968
Accession: P35968
Background: Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. It also plays an essential role in promoting proliferation, survival, migration and differentiation of endothelial cells, reorganization of the actin cytoskeleton. VEGFR2 is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo.The adaptor protein SHB has been shown to interact with VEGFR2 in receptor tyrosine kinase signaling. In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
Concentration:
Activity: Not validated for activity
Sequence: Ala20-Glu764
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 86.1 kDa
ObservedMW: 120-150 kDa
Original: $737.62
-70%$737.62
$221.29Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: VEGF R2;FLK-1;KDR
Target Synonym: FLK-1;Fetal liver kinase 1;KDR;Kinase insert domain receptor;Protein-tyrosine kinase receptor flk-1;VEGF R2;VEGFR-2;VEGFR2;Vascular endothelial growth factor receptor 2
Research Areas: Signal Transduction;Microbiology;Cardiovascular;Cancer;metabolism;Stem cells
Conjugation: Biotinylated
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His-Avi
UNIProt ID: P35968
Accession: P35968
Background: Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. It also plays an essential role in promoting proliferation, survival, migration and differentiation of endothelial cells, reorganization of the actin cytoskeleton. VEGFR2 is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo.The adaptor protein SHB has been shown to interact with VEGFR2 in receptor tyrosine kinase signaling. In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
Concentration:
Activity: Not validated for activity
Sequence: Ala20-Glu764
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 86.1 kDa
ObservedMW: 120-150 kDa
