Recombinant Human SUMO1 Protein (His Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: SUMO1
Target Synonym: DAP1;GAP-Modifying Protein 1;GMP1;OFC10;SENP2;SMT3;SMT3 Homolog 3;SMT3C;SMT3H3;SUMO-1;SUMO1;Sentrin;Small Ubiquitin-Related Modifier 1;Smt3C;UBL1;Ubiquitin-Homology Domain Protein PIC1;Ubiquitin-Like Protein;Ubiquitin-Like Protein SMT3C
Research Areas: Cell biology;Cardiovascular;Cancer;metabolism
Conjugation:
Target Species: Human
Expression Host: E.coli
Application:
Fusion tag: N-His
UNIProt ID: P63165
Accession: AAH66306
Background: Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.
Concentration:
Activity: Not validated for activity
Sequence: Met 1-Val101
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.5 .
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 13.7 kDa
ObservedMW: 17-19 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Human SUMO1 Protein (His Tag)
Recombinant Human SUMO1 Protein (His Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: SUMO1
Target Synonym: DAP1;GAP-Modifying Protein 1;GMP1;OFC10;SENP2;SMT3;SMT3 Homolog 3;SMT3C;SMT3H3;SUMO-1;SUMO1;Sentrin;Small Ubiquitin-Related Modifier 1;Smt3C;UBL1;Ubiquitin-Homology Domain Protein PIC1;Ubiquitin-Like Protein;Ubiquitin-Like Protein SMT3C
Research Areas: Cell biology;Cardiovascular;Cancer;metabolism
Conjugation:
Target Species: Human
Expression Host: E.coli
Application:
Fusion tag: N-His
UNIProt ID: P63165
Accession: AAH66306
Background: Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.
Concentration:
Activity: Not validated for activity
Sequence: Met 1-Val101
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.5 .
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 13.7 kDa
ObservedMW: 17-19 kDa
Original: $115.18
-70%$115.18
$34.55Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: SUMO1
Target Synonym: DAP1;GAP-Modifying Protein 1;GMP1;OFC10;SENP2;SMT3;SMT3 Homolog 3;SMT3C;SMT3H3;SUMO-1;SUMO1;Sentrin;Small Ubiquitin-Related Modifier 1;Smt3C;UBL1;Ubiquitin-Homology Domain Protein PIC1;Ubiquitin-Like Protein;Ubiquitin-Like Protein SMT3C
Research Areas: Cell biology;Cardiovascular;Cancer;metabolism
Conjugation:
Target Species: Human
Expression Host: E.coli
Application:
Fusion tag: N-His
UNIProt ID: P63165
Accession: AAH66306
Background: Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.
Concentration:
Activity: Not validated for activity
Sequence: Met 1-Val101
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.5 .
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 13.7 kDa
ObservedMW: 17-19 kDa
