HomeStore

Recombinant Human NSE/ENO2 Protein (His Tag)

Product image 1

Recombinant Human NSE/ENO2 Protein (His Tag)

Recombinant Human NSE/ENO2 Protein (His Tag)

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: NSE;ENO2

Target Synonym: 2-phospho-D-glycerate hydro-lyase;ENO2;Enolase 2;Gamma-enolase;NSE;Neural enolase;Neuron-specific enolase

Research Areas: Signal Transduction;Tags & Cell Markers;Neuroscience;Cancer;Developmental Biology;epigenetics and nuclear signal;metabolism;Stem cells

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: P09104

Accession: P09104

Background: Gamma-enolase; also known as Enolase 2; belongs to the enolase family. The alpha/alpha homodimer of ENO2 is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle; and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. During ontogenesis; there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells; and to the alpha/gamma heterodimer in nerve cells. Levels of ENO2 increase dramatically in cardiovascular accidents; cerebral trauma; brain tumors and Creutzfeldt-Jakob disease. ENO2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. It binds to cultured neocortical neurons and promotes cell survival in a calcium-dependent manner.

Concentration:

Activity: Not validated for activity

Sequence: Met1-Leu434

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 8% Sucrose, 0.05% Tween 80, pH 7.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 49.4 kDa

ObservedMW: 55 kDa

$1,885,365.36

Original: $6,284,551.20

-70%
Recombinant Human NSE/ENO2 Protein (His Tag)

$6,284,551.20

$1,885,365.36

Product Information

Shipping & Returns

Description

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: NSE;ENO2

Target Synonym: 2-phospho-D-glycerate hydro-lyase;ENO2;Enolase 2;Gamma-enolase;NSE;Neural enolase;Neuron-specific enolase

Research Areas: Signal Transduction;Tags & Cell Markers;Neuroscience;Cancer;Developmental Biology;epigenetics and nuclear signal;metabolism;Stem cells

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: P09104

Accession: P09104

Background: Gamma-enolase; also known as Enolase 2; belongs to the enolase family. The alpha/alpha homodimer of ENO2 is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle; and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. During ontogenesis; there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells; and to the alpha/gamma heterodimer in nerve cells. Levels of ENO2 increase dramatically in cardiovascular accidents; cerebral trauma; brain tumors and Creutzfeldt-Jakob disease. ENO2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. It binds to cultured neocortical neurons and promotes cell survival in a calcium-dependent manner.

Concentration:

Activity: Not validated for activity

Sequence: Met1-Leu434

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 8% Sucrose, 0.05% Tween 80, pH 7.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 49.4 kDa

ObservedMW: 55 kDa