Recombinant Human Nectin-4/NECTIN4 Protein (His Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: Nectin-4;NECTIN4
Target Synonym: Ig superfamily receptor LNIR;LNIR;Nectin-4;PRR4;PVRL4;Poliovirus receptor-related protein 4
Research Areas: Cell biology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application: ELISA
Fusion tag: C-His
UNIProt ID: Q96NY8
Accession: Q96NY8
Background: Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.
Concentration:
Activity: Immobilized Anti-Human Nectin-4 mAb-mFc at 2μg/ml (100 μl/well) can bind Human Nectin-4-His.The ED50 of Human Nectin-4-His is 16.29 ng/ml.
Sequence: Gly32-Val351
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 35.3 kDa
ObservedMW: 40-47 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Human Nectin-4/NECTIN4 Protein (His Tag)
Recombinant Human Nectin-4/NECTIN4 Protein (His Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: Nectin-4;NECTIN4
Target Synonym: Ig superfamily receptor LNIR;LNIR;Nectin-4;PRR4;PVRL4;Poliovirus receptor-related protein 4
Research Areas: Cell biology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application: ELISA
Fusion tag: C-His
UNIProt ID: Q96NY8
Accession: Q96NY8
Background: Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.
Concentration:
Activity: Immobilized Anti-Human Nectin-4 mAb-mFc at 2μg/ml (100 μl/well) can bind Human Nectin-4-His.The ED50 of Human Nectin-4-His is 16.29 ng/ml.
Sequence: Gly32-Val351
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 35.3 kDa
ObservedMW: 40-47 kDa
Original: $3,475,958.97
-70%$3,475,958.97
$1,042,787.69Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: Nectin-4;NECTIN4
Target Synonym: Ig superfamily receptor LNIR;LNIR;Nectin-4;PRR4;PVRL4;Poliovirus receptor-related protein 4
Research Areas: Cell biology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application: ELISA
Fusion tag: C-His
UNIProt ID: Q96NY8
Accession: Q96NY8
Background: Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.
Concentration:
Activity: Immobilized Anti-Human Nectin-4 mAb-mFc at 2μg/ml (100 μl/well) can bind Human Nectin-4-His.The ED50 of Human Nectin-4-His is 16.29 ng/ml.
Sequence: Gly32-Val351
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 35.3 kDa
ObservedMW: 40-47 kDa
