Recombinant Human MAN1B1 Protein (His Tag)
Size: 50μg
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: MAN1B1
Target Synonym: 2-Alpha-Mannosidase;2-Mannosidase;ER Alpha-1;ER Mannosidase 1;ERMan1;Endoplasmic Reticulum Mannosyl-Oligosaccharide 1;MAN1B1;Man9GlcNAc2-Specific-Processing Alpha-Mannosidase;Mannosidase Alpha Class 1B Member 1
Research Areas: Tags & Cell Markers
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: Q9UKM7
Accession: Q9UKM7
Background: Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period.
Concentration:
Activity: Not validated for activity
Sequence: Asp106-Ala699
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl,10mM reduced Glutathione,pH 8.0.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 68.7 kDa
ObservedMW: 58-80 kDa
Product Information
Product Information
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Recombinant Human MAN1B1 Protein (His Tag)
Recombinant Human MAN1B1 Protein (His Tag)
Size: 50μg
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: MAN1B1
Target Synonym: 2-Alpha-Mannosidase;2-Mannosidase;ER Alpha-1;ER Mannosidase 1;ERMan1;Endoplasmic Reticulum Mannosyl-Oligosaccharide 1;MAN1B1;Man9GlcNAc2-Specific-Processing Alpha-Mannosidase;Mannosidase Alpha Class 1B Member 1
Research Areas: Tags & Cell Markers
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: Q9UKM7
Accession: Q9UKM7
Background: Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period.
Concentration:
Activity: Not validated for activity
Sequence: Asp106-Ala699
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl,10mM reduced Glutathione,pH 8.0.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 68.7 kDa
ObservedMW: 58-80 kDa
Original: $761.57
-70%$761.57
$228.47Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: MAN1B1
Target Synonym: 2-Alpha-Mannosidase;2-Mannosidase;ER Alpha-1;ER Mannosidase 1;ERMan1;Endoplasmic Reticulum Mannosyl-Oligosaccharide 1;MAN1B1;Man9GlcNAc2-Specific-Processing Alpha-Mannosidase;Mannosidase Alpha Class 1B Member 1
Research Areas: Tags & Cell Markers
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: Q9UKM7
Accession: Q9UKM7
Background: Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period.
Concentration:
Activity: Not validated for activity
Sequence: Asp106-Ala699
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl,10mM reduced Glutathione,pH 8.0.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 68.7 kDa
ObservedMW: 58-80 kDa
