Recombinant Human LMCD1/Dyxin Protein (His Tag)
Size: 50μg
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: LMCD1;Dyxin
Target Synonym: Dyxin;LIM and cysteine-rich domains protein 1;LMCD1
Research Areas: Signal Transduction;Neuroscience;
Conjugation:
Target Species: Human
Expression Host: E.coli
Application:
Fusion tag: N-His & C-His
UNIProt ID: Q9NZU5
Accession: Q9NZU5
Background: LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Concentration:
Activity: Not validated for activity
Sequence: Met 1-Ser365
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, pH 8.0.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 44.0 kDa
ObservedMW: 45 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Human LMCD1/Dyxin Protein (His Tag)
Recombinant Human LMCD1/Dyxin Protein (His Tag)
Size: 50μg
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: LMCD1;Dyxin
Target Synonym: Dyxin;LIM and cysteine-rich domains protein 1;LMCD1
Research Areas: Signal Transduction;Neuroscience;
Conjugation:
Target Species: Human
Expression Host: E.coli
Application:
Fusion tag: N-His & C-His
UNIProt ID: Q9NZU5
Accession: Q9NZU5
Background: LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Concentration:
Activity: Not validated for activity
Sequence: Met 1-Ser365
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, pH 8.0.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 44.0 kDa
ObservedMW: 45 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: LMCD1;Dyxin
Target Synonym: Dyxin;LIM and cysteine-rich domains protein 1;LMCD1
Research Areas: Signal Transduction;Neuroscience;
Conjugation:
Target Species: Human
Expression Host: E.coli
Application:
Fusion tag: N-His & C-His
UNIProt ID: Q9NZU5
Accession: Q9NZU5
Background: LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Concentration:
Activity: Not validated for activity
Sequence: Met 1-Ser365
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, pH 8.0.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 44.0 kDa
ObservedMW: 45 kDa
