Recombinant Human Interleukin-33/IL-33 Protein (His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: Interleukin-33;IL-33
Target Synonym: DVS;IL1F;Interleukin;C9orf;IL-1F;IL33;C9orf26;DVS27;IL1F11;NF-HEV;NFEHEV;DVS27 related protein;IL-1F11;IL-33;Interleukin-1 family member 11;Interleukin-33;Nuclear factor from high endothelial venules;NFHEV;CHROMOSOME 9 OPEN READING FRAME 26;DKFZp586H0523;IL 1F11;IL 33;Interleukin 1 family member 11;Interleukin 33;INTERLEUKIN 33 NFHEV;Interleukin 33 precursor;Interleukin33;Interleukin-33 (109-270);NF HEV;Nuclear factor for high endothelial venules;OTTHUMP00000021041;RP11 575C20.2
Research Areas: Cardiovascular;immunology
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: O95760
Accession: O95760
Background: Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils; Peyer patches and mesenteric lymph nodes; but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP); activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
Concentration:
Activity: Measure by its ability to binding with recombinant ST2L (IL-33 receptor). The ED50 for this effect is <54 ng/mL.Measure by its ability to induce proliferation in D10.G4.1 cells. The ED50 for this effect is < 0.1 ng/mL. The specific activity of recombinant human IL-33 is approximately >4 x107 IU/ mg.
Sequence: Ser112-Thr 270
Purity: > 98 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 18.9 kDa
ObservedMW: 19 kDa
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Recombinant Human Interleukin-33/IL-33 Protein (His Tag)
Recombinant Human Interleukin-33/IL-33 Protein (His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: Interleukin-33;IL-33
Target Synonym: DVS;IL1F;Interleukin;C9orf;IL-1F;IL33;C9orf26;DVS27;IL1F11;NF-HEV;NFEHEV;DVS27 related protein;IL-1F11;IL-33;Interleukin-1 family member 11;Interleukin-33;Nuclear factor from high endothelial venules;NFHEV;CHROMOSOME 9 OPEN READING FRAME 26;DKFZp586H0523;IL 1F11;IL 33;Interleukin 1 family member 11;Interleukin 33;INTERLEUKIN 33 NFHEV;Interleukin 33 precursor;Interleukin33;Interleukin-33 (109-270);NF HEV;Nuclear factor for high endothelial venules;OTTHUMP00000021041;RP11 575C20.2
Research Areas: Cardiovascular;immunology
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: O95760
Accession: O95760
Background: Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils; Peyer patches and mesenteric lymph nodes; but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP); activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
Concentration:
Activity: Measure by its ability to binding with recombinant ST2L (IL-33 receptor). The ED50 for this effect is <54 ng/mL.Measure by its ability to induce proliferation in D10.G4.1 cells. The ED50 for this effect is < 0.1 ng/mL. The specific activity of recombinant human IL-33 is approximately >4 x107 IU/ mg.
Sequence: Ser112-Thr 270
Purity: > 98 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 18.9 kDa
ObservedMW: 19 kDa
Original: $9,128,649.38
-70%$9,128,649.38
$2,738,594.81Product Information
Product Information
Shipping & Returns
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Description
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: Interleukin-33;IL-33
Target Synonym: DVS;IL1F;Interleukin;C9orf;IL-1F;IL33;C9orf26;DVS27;IL1F11;NF-HEV;NFEHEV;DVS27 related protein;IL-1F11;IL-33;Interleukin-1 family member 11;Interleukin-33;Nuclear factor from high endothelial venules;NFHEV;CHROMOSOME 9 OPEN READING FRAME 26;DKFZp586H0523;IL 1F11;IL 33;Interleukin 1 family member 11;Interleukin 33;INTERLEUKIN 33 NFHEV;Interleukin 33 precursor;Interleukin33;Interleukin-33 (109-270);NF HEV;Nuclear factor for high endothelial venules;OTTHUMP00000021041;RP11 575C20.2
Research Areas: Cardiovascular;immunology
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: O95760
Accession: O95760
Background: Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils; Peyer patches and mesenteric lymph nodes; but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP); activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
Concentration:
Activity: Measure by its ability to binding with recombinant ST2L (IL-33 receptor). The ED50 for this effect is <54 ng/mL.Measure by its ability to induce proliferation in D10.G4.1 cells. The ED50 for this effect is < 0.1 ng/mL. The specific activity of recombinant human IL-33 is approximately >4 x107 IU/ mg.
Sequence: Ser112-Thr 270
Purity: > 98 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 18.9 kDa
ObservedMW: 19 kDa
