Recombinant Human IL10RB/IL10R2 Protein (Fc Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: IL10RB;IL10R2
Target Synonym: CRFB;Interleukin-10 receptor subunit;Cytokine receptor class-II member;Cytokine receptor family 2 member;CRF2;IL-10R;CDW210B;CRF2-4;Cytokine receptor class-II member 4;Cytokine receptor family 2 member 4;IL-10R2;Interleukin-10 receptor subunit 2;Interleukin-10 receptor subunit beta(IL10RB);IL10RB;CRFB4;D21S58;D21S66; CRF2-4; IL-10Rb;Cd210;CRF2 4;Cytokine receptor class II;Cytokine receptor class II CRF2 4;Cytokine receptor family II member 4;I10R2;IL-10 receptor subunit beta;IL-10R subunit 2;IL-10R subunit beta;IL10R2;IL-10RB;Interleukin 10 receptor beta;Interleukin-10 receptor subunit beta
Research Areas: Signal Transduction;immunology;
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-Fc
UNIProt ID: Q08334
Accession: Q08334
Background: Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
Concentration:
Activity: Not validated for activity
Sequence: Met20-Ser220
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 50.6 kDa
ObservedMW: 75-95 kDa
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Recombinant Human IL10RB/IL10R2 Protein (Fc Tag)
Recombinant Human IL10RB/IL10R2 Protein (Fc Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: IL10RB;IL10R2
Target Synonym: CRFB;Interleukin-10 receptor subunit;Cytokine receptor class-II member;Cytokine receptor family 2 member;CRF2;IL-10R;CDW210B;CRF2-4;Cytokine receptor class-II member 4;Cytokine receptor family 2 member 4;IL-10R2;Interleukin-10 receptor subunit 2;Interleukin-10 receptor subunit beta(IL10RB);IL10RB;CRFB4;D21S58;D21S66; CRF2-4; IL-10Rb;Cd210;CRF2 4;Cytokine receptor class II;Cytokine receptor class II CRF2 4;Cytokine receptor family II member 4;I10R2;IL-10 receptor subunit beta;IL-10R subunit 2;IL-10R subunit beta;IL10R2;IL-10RB;Interleukin 10 receptor beta;Interleukin-10 receptor subunit beta
Research Areas: Signal Transduction;immunology;
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-Fc
UNIProt ID: Q08334
Accession: Q08334
Background: Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
Concentration:
Activity: Not validated for activity
Sequence: Met20-Ser220
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 50.6 kDa
ObservedMW: 75-95 kDa
Original: $2,247,018.71
-70%$2,247,018.71
$674,105.61Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: IL10RB;IL10R2
Target Synonym: CRFB;Interleukin-10 receptor subunit;Cytokine receptor class-II member;Cytokine receptor family 2 member;CRF2;IL-10R;CDW210B;CRF2-4;Cytokine receptor class-II member 4;Cytokine receptor family 2 member 4;IL-10R2;Interleukin-10 receptor subunit 2;Interleukin-10 receptor subunit beta(IL10RB);IL10RB;CRFB4;D21S58;D21S66; CRF2-4; IL-10Rb;Cd210;CRF2 4;Cytokine receptor class II;Cytokine receptor class II CRF2 4;Cytokine receptor family II member 4;I10R2;IL-10 receptor subunit beta;IL-10R subunit 2;IL-10R subunit beta;IL10R2;IL-10RB;Interleukin 10 receptor beta;Interleukin-10 receptor subunit beta
Research Areas: Signal Transduction;immunology;
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-Fc
UNIProt ID: Q08334
Accession: Q08334
Background: Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
Concentration:
Activity: Not validated for activity
Sequence: Met20-Ser220
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 50.6 kDa
ObservedMW: 75-95 kDa
