Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: IL-1
Target Synonym: IL1F;IL-1F;pro IL1F;IL-1;IL1-BETA;IL1F2;IL1 beta;IL1B;catabolin;IL-1B;pro Catabolin;pro IL1B;pro IL1F2;pro leukocytic endogenous mediator;pro leukocytic pyrogen;pro lymphocyte activating factor;pro mononuclear cell factor;IL-1F2;IL 1B;IL-1 beta
Research Areas: Cardiovascular;immunology;metabolism
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: ELISA
Fusion tag: N-His
UNIProt ID: P01584
Accession: NP_000567.1
Background: Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
Concentration:
Activity: Immobilized human IL1B at 10 μg/mL (100 μl/well) can bind human IL1R1.The EC50 of human IL1R1 is 0.198 μg/mL.
Sequence: Met 1-Ser 269(Glu6Lys)
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 32.3 kDa
ObservedMW: 34 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag)
Recombinant Human IL-1 beta/IL1B Protein (pro form, His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: IL-1
Target Synonym: IL1F;IL-1F;pro IL1F;IL-1;IL1-BETA;IL1F2;IL1 beta;IL1B;catabolin;IL-1B;pro Catabolin;pro IL1B;pro IL1F2;pro leukocytic endogenous mediator;pro leukocytic pyrogen;pro lymphocyte activating factor;pro mononuclear cell factor;IL-1F2;IL 1B;IL-1 beta
Research Areas: Cardiovascular;immunology;metabolism
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: ELISA
Fusion tag: N-His
UNIProt ID: P01584
Accession: NP_000567.1
Background: Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
Concentration:
Activity: Immobilized human IL1B at 10 μg/mL (100 μl/well) can bind human IL1R1.The EC50 of human IL1R1 is 0.198 μg/mL.
Sequence: Met 1-Ser 269(Glu6Lys)
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 32.3 kDa
ObservedMW: 34 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: IL-1
Target Synonym: IL1F;IL-1F;pro IL1F;IL-1;IL1-BETA;IL1F2;IL1 beta;IL1B;catabolin;IL-1B;pro Catabolin;pro IL1B;pro IL1F2;pro leukocytic endogenous mediator;pro leukocytic pyrogen;pro lymphocyte activating factor;pro mononuclear cell factor;IL-1F2;IL 1B;IL-1 beta
Research Areas: Cardiovascular;immunology;metabolism
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: ELISA
Fusion tag: N-His
UNIProt ID: P01584
Accession: NP_000567.1
Background: Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
Concentration:
Activity: Immobilized human IL1B at 10 μg/mL (100 μl/well) can bind human IL1R1.The EC50 of human IL1R1 is 0.198 μg/mL.
Sequence: Met 1-Ser 269(Glu6Lys)
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 32.3 kDa
ObservedMW: 34 kDa
