Recombinant Human IDH1 Protein (Human Cells, His Tag)
Size: 50μg
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: IDH1
Target Synonym: Cytosolic NADP-Isocitrate Dehydrogenase;IDH;IDH1;IDP;Isocitrate Dehydrogenase [NADP] Cytoplasmic;NADP(+)-Specific ICDH;Oxalosuccinate Decarboxylase;PICD
Research Areas: Signal Transduction;Cancer;metabolism;
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: O75874
Accession: O75874
Background: Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions; such as the conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; as well as in peroxisomal reactions that consume 2-oxoglutarate; namely the α-hydroxylation of phytanic acid.
Concentration:
Activity: Not validated for activity
Sequence: Met 1-Leu414
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.05% Brij-35, 10% Glycerol, 1mM DTT, pH8.0.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 47.7 kDa
ObservedMW: 45 kDa
Product Information
Product Information
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Shipping & Returns
Recombinant Human IDH1 Protein (Human Cells, His Tag)
Recombinant Human IDH1 Protein (Human Cells, His Tag)
Size: 50μg
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: IDH1
Target Synonym: Cytosolic NADP-Isocitrate Dehydrogenase;IDH;IDH1;IDP;Isocitrate Dehydrogenase [NADP] Cytoplasmic;NADP(+)-Specific ICDH;Oxalosuccinate Decarboxylase;PICD
Research Areas: Signal Transduction;Cancer;metabolism;
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: O75874
Accession: O75874
Background: Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions; such as the conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; as well as in peroxisomal reactions that consume 2-oxoglutarate; namely the α-hydroxylation of phytanic acid.
Concentration:
Activity: Not validated for activity
Sequence: Met 1-Leu414
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.05% Brij-35, 10% Glycerol, 1mM DTT, pH8.0.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 47.7 kDa
ObservedMW: 45 kDa
Original: $1,376.76
-70%$1,376.76
$413.03Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: IDH1
Target Synonym: Cytosolic NADP-Isocitrate Dehydrogenase;IDH;IDH1;IDP;Isocitrate Dehydrogenase [NADP] Cytoplasmic;NADP(+)-Specific ICDH;Oxalosuccinate Decarboxylase;PICD
Research Areas: Signal Transduction;Cancer;metabolism;
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: O75874
Accession: O75874
Background: Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions; such as the conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; as well as in peroxisomal reactions that consume 2-oxoglutarate; namely the α-hydroxylation of phytanic acid.
Concentration:
Activity: Not validated for activity
Sequence: Met 1-Leu414
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.05% Brij-35, 10% Glycerol, 1mM DTT, pH8.0.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 47.7 kDa
ObservedMW: 45 kDa
