Recombinant Human GDNF Protein
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: GDNF
Target Synonym: ATF;Astrocyte-Derived Trophic Factor;GDNF;Glial Cell Line-Derived Neurotrophic Factor;hGDNF
Research Areas: Neuroscience;Developmental Biology
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: P39905
Accession: P39905
Background: Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF-β superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease.
Concentration:
Activity: Measure by its ability to induce proliferation in SH-SY5Y cells. The ED50 for this effect is <10 ng/mL.
Sequence: Ser78-Ile211
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 16.0 kDa
ObservedMW: 16 kDa
Product Information
Product Information
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Shipping & Returns
Recombinant Human GDNF Protein
Recombinant Human GDNF Protein
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: GDNF
Target Synonym: ATF;Astrocyte-Derived Trophic Factor;GDNF;Glial Cell Line-Derived Neurotrophic Factor;hGDNF
Research Areas: Neuroscience;Developmental Biology
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: P39905
Accession: P39905
Background: Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF-β superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease.
Concentration:
Activity: Measure by its ability to induce proliferation in SH-SY5Y cells. The ED50 for this effect is <10 ng/mL.
Sequence: Ser78-Ile211
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 16.0 kDa
ObservedMW: 16 kDa
Original: $9,128,649.38
-70%$9,128,649.38
$2,738,594.81Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: GDNF
Target Synonym: ATF;Astrocyte-Derived Trophic Factor;GDNF;Glial Cell Line-Derived Neurotrophic Factor;hGDNF
Research Areas: Neuroscience;Developmental Biology
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: P39905
Accession: P39905
Background: Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF-β superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease.
Concentration:
Activity: Measure by its ability to induce proliferation in SH-SY5Y cells. The ED50 for this effect is <10 ng/mL.
Sequence: Ser78-Ile211
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 16.0 kDa
ObservedMW: 16 kDa
