Recombinant Human Dectin-1/CLEC7A Protein (Fc Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: Dectin-1;CLEC7A
Target Synonym: BGR;Beta-glucan receptor;CANDF4;CD369;CLEC7A;CLECSF12;CLECSF12DC-associated C-type lectin 1;DECTIN1;DECTIN1CANDF4;Dectin-1;Dectin1
Research Areas: immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: N-Fc
UNIProt ID: Q9BXN2
Accession: Q9BXN2
Background: Dectin-1 was recently identified as the most important receptor for beta-glucan. It is a type II transmembrane protein which binds beta-1,3 and beta-1,6 glucans, and is expressed on most cells of the innate immune system and has been implicated in phagocytosis as well as killing of fungi by macrophages, neutrophils and dendritic cells. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against opportunistic fungal infection.
Concentration:
Activity: Not validated for activity
Sequence: Thr66-Met247
Purity: > 85 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 46.9 kDa
ObservedMW: 50-65 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Human Dectin-1/CLEC7A Protein (Fc Tag)
Recombinant Human Dectin-1/CLEC7A Protein (Fc Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: Dectin-1;CLEC7A
Target Synonym: BGR;Beta-glucan receptor;CANDF4;CD369;CLEC7A;CLECSF12;CLECSF12DC-associated C-type lectin 1;DECTIN1;DECTIN1CANDF4;Dectin-1;Dectin1
Research Areas: immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: N-Fc
UNIProt ID: Q9BXN2
Accession: Q9BXN2
Background: Dectin-1 was recently identified as the most important receptor for beta-glucan. It is a type II transmembrane protein which binds beta-1,3 and beta-1,6 glucans, and is expressed on most cells of the innate immune system and has been implicated in phagocytosis as well as killing of fungi by macrophages, neutrophils and dendritic cells. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against opportunistic fungal infection.
Concentration:
Activity: Not validated for activity
Sequence: Thr66-Met247
Purity: > 85 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 46.9 kDa
ObservedMW: 50-65 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: Dectin-1;CLEC7A
Target Synonym: BGR;Beta-glucan receptor;CANDF4;CD369;CLEC7A;CLECSF12;CLECSF12DC-associated C-type lectin 1;DECTIN1;DECTIN1CANDF4;Dectin-1;Dectin1
Research Areas: immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: N-Fc
UNIProt ID: Q9BXN2
Accession: Q9BXN2
Background: Dectin-1 was recently identified as the most important receptor for beta-glucan. It is a type II transmembrane protein which binds beta-1,3 and beta-1,6 glucans, and is expressed on most cells of the innate immune system and has been implicated in phagocytosis as well as killing of fungi by macrophages, neutrophils and dendritic cells. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against opportunistic fungal infection.
Concentration:
Activity: Not validated for activity
Sequence: Thr66-Met247
Purity: > 85 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 46.9 kDa
ObservedMW: 50-65 kDa
