Recombinant Human CD82 (N-Fc)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: CD82
Target Synonym: CD82;CD82 antigenC33;CD82 molecule;IA4;IA4C33 antigen;Inducible membrane protein R2;KAI1;KAI1GR15;ST6;ST6tspan-27;Suppressor of tumorigenicity 6 protein;TSPAN27;TSPAN274F9;Tetraspanin-27;Tspan-27
Research Areas: Cancer;epigenetics and nuclear signal;immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: N-Fc
UNIProt ID: P27701
Accession: P27701
Background: CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
Concentration:
Activity: Not validated for activity
Sequence: Gly103-Gln225
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 40.3 kDa
ObservedMW: 40-60 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Human CD82 (N-Fc)
Recombinant Human CD82 (N-Fc)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: CD82
Target Synonym: CD82;CD82 antigenC33;CD82 molecule;IA4;IA4C33 antigen;Inducible membrane protein R2;KAI1;KAI1GR15;ST6;ST6tspan-27;Suppressor of tumorigenicity 6 protein;TSPAN27;TSPAN274F9;Tetraspanin-27;Tspan-27
Research Areas: Cancer;epigenetics and nuclear signal;immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: N-Fc
UNIProt ID: P27701
Accession: P27701
Background: CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
Concentration:
Activity: Not validated for activity
Sequence: Gly103-Gln225
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 40.3 kDa
ObservedMW: 40-60 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: CD82
Target Synonym: CD82;CD82 antigenC33;CD82 molecule;IA4;IA4C33 antigen;Inducible membrane protein R2;KAI1;KAI1GR15;ST6;ST6tspan-27;Suppressor of tumorigenicity 6 protein;TSPAN27;TSPAN274F9;Tetraspanin-27;Tspan-27
Research Areas: Cancer;epigenetics and nuclear signal;immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: N-Fc
UNIProt ID: P27701
Accession: P27701
Background: CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
Concentration:
Activity: Not validated for activity
Sequence: Gly103-Gln225
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 40.3 kDa
ObservedMW: 40-60 kDa
