Recombinant Human CD47/IAP/OA3 (C-Avi-6His) Biotinylated
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Immune Checkpoint Proteins
Abbreviation: Human CD47;IAP;OA3
Target Synonym: Antigenic Surface Determinant Protein OA3;CD47;IAP;Integrin-Associated Protein;Leukocyte Surface Antigen CD47;MER6;Protein MER6
Research Areas: Cancer;immunology
Conjugation: Biotinylated
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-Avi-His
UNIProt ID: Q08722
Accession: Q08722
Background: CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.
Concentration:
Activity: Not validated for activity
Sequence: Gln19-Pro139
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 10mMTris-Citrate, 150mM NaCl, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 16.4 kDa
ObservedMW: 30-40 kDa
Product Information
Product Information
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Shipping & Returns
Recombinant Human CD47/IAP/OA3 (C-Avi-6His) Biotinylated
Recombinant Human CD47/IAP/OA3 (C-Avi-6His) Biotinylated
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Immune Checkpoint Proteins
Abbreviation: Human CD47;IAP;OA3
Target Synonym: Antigenic Surface Determinant Protein OA3;CD47;IAP;Integrin-Associated Protein;Leukocyte Surface Antigen CD47;MER6;Protein MER6
Research Areas: Cancer;immunology
Conjugation: Biotinylated
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-Avi-His
UNIProt ID: Q08722
Accession: Q08722
Background: CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.
Concentration:
Activity: Not validated for activity
Sequence: Gln19-Pro139
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 10mMTris-Citrate, 150mM NaCl, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 16.4 kDa
ObservedMW: 30-40 kDa
Original: $737.62
-70%$737.62
$221.29Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Immune Checkpoint Proteins
Abbreviation: Human CD47;IAP;OA3
Target Synonym: Antigenic Surface Determinant Protein OA3;CD47;IAP;Integrin-Associated Protein;Leukocyte Surface Antigen CD47;MER6;Protein MER6
Research Areas: Cancer;immunology
Conjugation: Biotinylated
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-Avi-His
UNIProt ID: Q08722
Accession: Q08722
Background: CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.
Concentration:
Activity: Not validated for activity
Sequence: Gln19-Pro139
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 10mMTris-Citrate, 150mM NaCl, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 16.4 kDa
ObservedMW: 30-40 kDa
