Recombinant Human CD300a/LMIR1 Protein (Fc & His Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: CD300a;LMIR1
Target Synonym: CD300 Antigen-Like Family Member A;CD300A;CD300a;CLM-8;CMRF-35-H9;CMRF35-H;CMRF35-H9;CMRF35-Like Molecule 8;CMRF35H;IGSF12;IRC1/IRC2;IRp60;IgSF12;Immunoglobulin Superfamily Member 12;Inhibitory Receptor Protein 60;NK Inhibitory Receptor
Research Areas: immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-Fc-His
UNIProt ID: Q9UGN4
Accession: Q9UGN4
Background: CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b; CD300e) and inhibitory members (CD300a; CD300f); as well as molecules presenting a negative charge within their transmembrane domain (CD300c; CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets; B-cells; dendritic cells; mast cells; granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells; and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.
Concentration:
Activity: Not validated for activity
Sequence: Leu18-Gln178
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 45.4 kDa
ObservedMW: 60-75 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Human CD300a/LMIR1 Protein (Fc & His Tag)
Recombinant Human CD300a/LMIR1 Protein (Fc & His Tag)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: CD300a;LMIR1
Target Synonym: CD300 Antigen-Like Family Member A;CD300A;CD300a;CLM-8;CMRF-35-H9;CMRF35-H;CMRF35-H9;CMRF35-Like Molecule 8;CMRF35H;IGSF12;IRC1/IRC2;IRp60;IgSF12;Immunoglobulin Superfamily Member 12;Inhibitory Receptor Protein 60;NK Inhibitory Receptor
Research Areas: immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-Fc-His
UNIProt ID: Q9UGN4
Accession: Q9UGN4
Background: CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b; CD300e) and inhibitory members (CD300a; CD300f); as well as molecules presenting a negative charge within their transmembrane domain (CD300c; CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets; B-cells; dendritic cells; mast cells; granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells; and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.
Concentration:
Activity: Not validated for activity
Sequence: Leu18-Gln178
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 45.4 kDa
ObservedMW: 60-75 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: CD300a;LMIR1
Target Synonym: CD300 Antigen-Like Family Member A;CD300A;CD300a;CLM-8;CMRF-35-H9;CMRF35-H;CMRF35-H9;CMRF35-Like Molecule 8;CMRF35H;IGSF12;IRC1/IRC2;IRp60;IgSF12;Immunoglobulin Superfamily Member 12;Inhibitory Receptor Protein 60;NK Inhibitory Receptor
Research Areas: immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-Fc-His
UNIProt ID: Q9UGN4
Accession: Q9UGN4
Background: CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b; CD300e) and inhibitory members (CD300a; CD300f); as well as molecules presenting a negative charge within their transmembrane domain (CD300c; CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets; B-cells; dendritic cells; mast cells; granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells; and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.
Concentration:
Activity: Not validated for activity
Sequence: Leu18-Gln178
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 45.4 kDa
ObservedMW: 60-75 kDa
