Recombinant Human BMP-11 protein(His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: BMP-11
Target Synonym: GDF-11;Growth/Differentiation Factor-11
Research Areas: Signal Transduction,Cell Biology,Neuroscience
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: O95390
Accession: O95390
Background: Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.
Concentration:
Activity: Measure by its ability to induce alkaline phosphatase production by ATDC5 cells.The ED50 for this effect is <11 ng/mL.Measure by its ability to induce hemoglobin expression in K562 cells. The ED50 for this effect is <4 ng/mL.
Sequence: Asn 299-Ser 407
Purity: > 98 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 13.4 kDa
ObservedMW: 16 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Human BMP-11 protein(His Tag)
Recombinant Human BMP-11 protein(His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: BMP-11
Target Synonym: GDF-11;Growth/Differentiation Factor-11
Research Areas: Signal Transduction,Cell Biology,Neuroscience
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: O95390
Accession: O95390
Background: Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.
Concentration:
Activity: Measure by its ability to induce alkaline phosphatase production by ATDC5 cells.The ED50 for this effect is <11 ng/mL.Measure by its ability to induce hemoglobin expression in K562 cells. The ED50 for this effect is <4 ng/mL.
Sequence: Asn 299-Ser 407
Purity: > 98 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 13.4 kDa
ObservedMW: 16 kDa
Original: $468.06
-70%$468.06
$140.42Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: BMP-11
Target Synonym: GDF-11;Growth/Differentiation Factor-11
Research Areas: Signal Transduction,Cell Biology,Neuroscience
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: O95390
Accession: O95390
Background: Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.
Concentration:
Activity: Measure by its ability to induce alkaline phosphatase production by ATDC5 cells.The ED50 for this effect is <11 ng/mL.Measure by its ability to induce hemoglobin expression in K562 cells. The ED50 for this effect is <4 ng/mL.
Sequence: Asn 299-Ser 407
Purity: > 98 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 13.4 kDa
ObservedMW: 16 kDa
