Recombinant Human Angiopoietin-Related Protein 4/ANGPTL4 (N-6His)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: ANGPTL4
Target Synonym: 425O18-1;Angiopoietin-like protein 4;Angiopoietin-related protein 4;Angptl4;Farp;Fasting-induced adipose factor;Fiaf;HFARP;Hepatic fibrinogen/angiopoietin-related protein;Ng27;Secreted protein Bk89
Research Areas: Cardiovascular;Cancer;metabolism
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: N-His
UNIProt ID: Q9BY76
Accession: Q9BY76
Background: Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
Concentration:
Activity: Not validated for activity
Sequence: Pro166-Ser406
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, pH7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 27.9 kDa
ObservedMW: 32-38 kDa
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Product Information
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Shipping & Returns
Recombinant Human Angiopoietin-Related Protein 4/ANGPTL4 (N-6His)
Recombinant Human Angiopoietin-Related Protein 4/ANGPTL4 (N-6His)
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: ANGPTL4
Target Synonym: 425O18-1;Angiopoietin-like protein 4;Angiopoietin-related protein 4;Angptl4;Farp;Fasting-induced adipose factor;Fiaf;HFARP;Hepatic fibrinogen/angiopoietin-related protein;Ng27;Secreted protein Bk89
Research Areas: Cardiovascular;Cancer;metabolism
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: N-His
UNIProt ID: Q9BY76
Accession: Q9BY76
Background: Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
Concentration:
Activity: Not validated for activity
Sequence: Pro166-Ser406
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, pH7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 27.9 kDa
ObservedMW: 32-38 kDa
Original: $2,247,018.71
-70%$2,247,018.71
$674,105.61Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Others
Abbreviation: ANGPTL4
Target Synonym: 425O18-1;Angiopoietin-like protein 4;Angiopoietin-related protein 4;Angptl4;Farp;Fasting-induced adipose factor;Fiaf;HFARP;Hepatic fibrinogen/angiopoietin-related protein;Ng27;Secreted protein Bk89
Research Areas: Cardiovascular;Cancer;metabolism
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: N-His
UNIProt ID: Q9BY76
Accession: Q9BY76
Background: Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
Concentration:
Activity: Not validated for activity
Sequence: Pro166-Ser406
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, pH7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 27.9 kDa
ObservedMW: 32-38 kDa
