Recombinant Human 4-1BBL/TNFSF9 Protein (His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Immune Checkpoint Proteins
Abbreviation: 4-1BBL;TNFSF9
Target Synonym: 4-1BB ligand;4-1BBL;TNFSF9;Tumor necrosis factor ligand superfamily member 9
Research Areas: Cancer;immunology
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: P41273
Accession: P41273
Background: Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain; placenta; lung; skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells; and is thought to be involved in T cell-tumor cell interaction.
Concentration:
Activity: Measure by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is 1-5 ng/mL.
Sequence: Arg71-Asp 140
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 20.4 kDa
ObservedMW: 20 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Recombinant Human 4-1BBL/TNFSF9 Protein (His Tag)
Recombinant Human 4-1BBL/TNFSF9 Protein (His Tag)
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Immune Checkpoint Proteins
Abbreviation: 4-1BBL;TNFSF9
Target Synonym: 4-1BB ligand;4-1BBL;TNFSF9;Tumor necrosis factor ligand superfamily member 9
Research Areas: Cancer;immunology
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: P41273
Accession: P41273
Background: Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain; placenta; lung; skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells; and is thought to be involved in T cell-tumor cell interaction.
Concentration:
Activity: Measure by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is 1-5 ng/mL.
Sequence: Arg71-Asp 140
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 20.4 kDa
ObservedMW: 20 kDa
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 100μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Immune Checkpoint Proteins
Abbreviation: 4-1BBL;TNFSF9
Target Synonym: 4-1BB ligand;4-1BBL;TNFSF9;Tumor necrosis factor ligand superfamily member 9
Research Areas: Cancer;immunology
Conjugation:
Target Species: Human
Expression Host: E.coli
Application: Cell culture
Fusion tag: C-His
UNIProt ID: P41273
Accession: P41273
Background: Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain; placenta; lung; skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells; and is thought to be involved in T cell-tumor cell interaction.
Concentration:
Activity: Measure by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is 1-5 ng/mL.
Sequence: Arg71-Asp 140
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
Calculated MW: 20.4 kDa
ObservedMW: 20 kDa
