pVHL Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: VHL
Target Synonym: Elongin binding protein;G7 protein;HRCA 1;HRCA1;Protein G7;pVHL;RCA 1;RCA1;VHL 1;VHL;VHL;VHL1;VHLH;Von Hippel Lindau disease tumor suppressor;von Hippel Lindau syndrome;von Hippel Lindau tumor suppressor;Von Hippel Lindau tumor suppressor;E3 ubiquitin protein ligase;Von Hippel-Lindau disease tumor suppressor
Research Areas: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P40337
Accession:
Background: Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human VHL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
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pVHL Polyclonal Antibody
pVHL Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: VHL
Target Synonym: Elongin binding protein;G7 protein;HRCA 1;HRCA1;Protein G7;pVHL;RCA 1;RCA1;VHL 1;VHL;VHL;VHL1;VHLH;Von Hippel Lindau disease tumor suppressor;von Hippel Lindau syndrome;von Hippel Lindau tumor suppressor;Von Hippel Lindau tumor suppressor;E3 ubiquitin protein ligase;Von Hippel-Lindau disease tumor suppressor
Research Areas: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P40337
Accession:
Background: Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human VHL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
Original: $1,534.73
-70%$1,534.73
$460.42Product Information
Product Information
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Description
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: VHL
Target Synonym: Elongin binding protein;G7 protein;HRCA 1;HRCA1;Protein G7;pVHL;RCA 1;RCA1;VHL 1;VHL;VHL;VHL1;VHLH;Von Hippel Lindau disease tumor suppressor;von Hippel Lindau syndrome;von Hippel Lindau tumor suppressor;Von Hippel Lindau tumor suppressor;E3 ubiquitin protein ligase;Von Hippel-Lindau disease tumor suppressor
Research Areas: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P40337
Accession:
Background: Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human VHL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
