Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PTN

Target Synonym: HARP;HB-GAM;HBBM;HBGAM;HBGF-8;HBGF8;HBNF;HBNF-1;HBNF1;heparin affin regulatory protein;Heparin binding growth associated molecule;Heparin binding growth factor 8;Heparin binding neurite outgrowth promoting factor 1;Heparin-binding brain mitogen;Heparin-binding growth factor 8;Heparin-binding growth-associated molecule;heparin-binding neurite outgrowth promoting factor;Heparin-binding neurite outgrowth-promoting factor 1;NEGF1;Neurite growth promoting factor 1;Neurite outgrowth-promoting factor;heparin-binding;OSF-1;OSF1;Osteoblast-specific factor 1;pleiotrophin (heparin binding growth factor 8;neurite growth-promoting factor 1);Pleiotrophin;PTN;PTN

Research Areas: Cancer;Immunology;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P21246

Accession:

Background: Pleiotrophin(PTN) also known asheparin-binding brain mitogen(HBBM) orheparin-binding growth factor 8(HBGF-8) orneurite growth-promoting factor 1(NEGF1) orheparin affinity regulatory peptide(HARP) orheparin binding growth associated molecule(HB-GAM) is aproteinthat in humans is encoded by thePTNgene.Pleiotrophin is an 18-kDagrowth factorthat has a high affinity forheparin. It is structurally related tomidkineandretinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human PTN

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 19kDa

ObservedMW: