Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PAICS

Target Synonym: ADE2;ADE2H1;AIR carboxylase;AIRC;DKFZp781N1372;MGC1343;MGC5024;Multifunctional protein ADE2;Multifunctional protein ADE2H1;Paics;PAIS;Phosphoribosylaminoimidazole carboxylase;Phosphoribosylaminoimidazole carboxylase;phosphoribosylaminoimidazole succinocarboxamide synthetase;PUR6;SAICAR synthetase

Research Areas: Epigenetics and Nuclear Signaling;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P22234

Accession:

Background: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.6 mg/mL

Immunogen: Recombinant protein of human PAICS

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 47kDa

ObservedMW: