Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MYSM1

Target Synonym: 2A-DUB;2ADUB;Histone H2A deubiquitinase;Histone H2A deubiquitinase MYSM1;KIAA1915;Myb like SWIRM and MPN domains 1;Myb like;SWIRM and MPN domain containing protein;Myb like;SWIRM and MPN domains 1;Myb-like;Myb-like;SWIRM and MPN domains 1;MYSM 1;mysm1;MYSM1 Myb-like;SWIRM and MPN domains 1;MYSM1;RP4-592A1.1;SWIRM and MPN domain-containing protein 1

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q5VVJ2

Accession:

Background: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Concentration: 0.7 mg/mL

Immunogen: Synthetic peptide of human MYSM1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 95kDa

ObservedMW: