Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MT-ND1

Target Synonym: Complex I;subunit ND1;Mitochondrially encoded NADH dehydrogenase 1;MT-ND1;MTND1;NAD1;NADH dehydrogenase subunit 1 (complex I);NADH dehydrogenase subunit 1;NADH-ubiquinone oxidoreductase chain 1;NADH-ubiquinone oxidoreductase;subunit ND1;NADH1;ND1;NU1M

Research Areas: Cancer;Metabolism;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P03886

Accession:

Background: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human MT-ND1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: