Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MMP8

Target Synonym: CLG 1;CLG1;Collagenase 1;Collagenase 1 neutrophil;HNC;Matrix metallopeptidase 8 (neutrophil collagenase);Matrix metalloprotease 8;Matrix metalloproteinase-8;MMP 8;MMP-8;Mmp8;MMP8;Neutrophil collagenase;PMNL CL;PMNL collagenase;PMNL-CL;PMNLCL

Research Areas: Cancer;Cell Biology;Cardiovascular;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P22894

Accession:

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human MMP8

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 53kDa

ObservedMW: