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MKP-2 Polyclonal Antibody

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MKP-2 Polyclonal Antibody

MKP-2 Polyclonal Antibody

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: DUSP4

Target Synonym: Dual specificity phosphatase 4;Dual specificity protein phosphatase 4;Dual specificity protein phosphatase hVH2;DUS4;DUSP 4;Dusp4;HVH 2;HVH2;MAP kinase phosphatase 2;Mitogen activated protein kinase phosphatase 2;Mitogen-activated protein kinase phosphatase 2;MKP 2;MKP-2;MKP2;Serine/threonine specific protein phosphatase;TYP;Typ1;VH 2;VH1 homologous phosphatase 2;VH2

Research Areas: Cancer;Cell Biology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q13115

Accession:

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

Concentration: 0.5 mg/mL

Immunogen: Recombinant protein of human DUSP4

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:150

Calculated MW: 43kDa

ObservedMW:

$460.42

Original: $1,534.73

-70%
MKP-2 Polyclonal Antibody

$1,534.73

$460.42

Product Information

Shipping & Returns

Description

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: DUSP4

Target Synonym: Dual specificity phosphatase 4;Dual specificity protein phosphatase 4;Dual specificity protein phosphatase hVH2;DUS4;DUSP 4;Dusp4;HVH 2;HVH2;MAP kinase phosphatase 2;Mitogen activated protein kinase phosphatase 2;Mitogen-activated protein kinase phosphatase 2;MKP 2;MKP-2;MKP2;Serine/threonine specific protein phosphatase;TYP;Typ1;VH 2;VH1 homologous phosphatase 2;VH2

Research Areas: Cancer;Cell Biology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q13115

Accession:

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

Concentration: 0.5 mg/mL

Immunogen: Recombinant protein of human DUSP4

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:150

Calculated MW: 43kDa

ObservedMW: