LRP2 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: LRP2
Target Synonym: Calcium sensor protein;DBS;Glycoprotein 330;gp330;Heymann nephritis antigen homolog;Low-density lipoprotein receptor-related protein 2;LRP-2;Lrp2;LRP2;Megalin
Research Areas: Cancer;Cardiovascular;Metabolism;Developmental Biology;Stem Cells
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P98164
Accession:
Background: The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).
Concentration: 0.5 mg/mL
Immunogen: Synthetic peptide of human LRP2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
Product Information
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LRP2 Polyclonal Antibody
LRP2 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: LRP2
Target Synonym: Calcium sensor protein;DBS;Glycoprotein 330;gp330;Heymann nephritis antigen homolog;Low-density lipoprotein receptor-related protein 2;LRP-2;Lrp2;LRP2;Megalin
Research Areas: Cancer;Cardiovascular;Metabolism;Developmental Biology;Stem Cells
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P98164
Accession:
Background: The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).
Concentration: 0.5 mg/mL
Immunogen: Synthetic peptide of human LRP2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
Original: $358.65
-70%$358.65
$107.59Product Information
Product Information
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Description
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: LRP2
Target Synonym: Calcium sensor protein;DBS;Glycoprotein 330;gp330;Heymann nephritis antigen homolog;Low-density lipoprotein receptor-related protein 2;LRP-2;Lrp2;LRP2;Megalin
Research Areas: Cancer;Cardiovascular;Metabolism;Developmental Biology;Stem Cells
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P98164
Accession:
Background: The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).
Concentration: 0.5 mg/mL
Immunogen: Synthetic peptide of human LRP2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
