Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: JNK2

Target Synonym: c Jun kinase 2;C Jun N terminal kinase 2;c-Jun N-terminal kinase 2;JNK 55;JNK-55;JNK2 alpha;JNK2;JNK2 beta;JNK2A;JNK2alpha;JNK2B;JNK2BETA;Jun kinase;MAP kinase 9;MAPK 9;Mapk9;Mitogen activated protein kinase 9;Mitogen-activated protein kinase 9;MK09;P54a;p54aSAPK;PRKM9;Protein kinase;mitogen-activated;9;SAPK alpha;SAPK;SAPK1a;Stress activated protein kinase 1a;Stress-activated protein kinase JNK2

Research Areas: Cancer;Cell Biology;Metabolism;Immunology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human ;Mouse ;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P45984

Accession:

Background: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human MAPK9

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 48kDa

ObservedMW: Refer to figures