JNK1/2/3 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: JNK1/2/3
Target Synonym: MAPK8;JNK1;PRKM8;SAPK1;SAPK1C;Mitogen-activated protein kinase 8;MAP kinase 8;MAPK 8;JNK-46;Stress-activated protein kinase 1c;SAPK1c;Stress-activated protein kinase JNK1;c-Jun N-terminal kinase 1;MAPK9;JNK2;PRKM9;SAPK1A;Mi
Research Areas: Cancer;Immunology;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat;Chicken
Application: WB;IHC-p;IF
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P45983,P45984,P53779
Accession:
Background: c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1α1,JNK1β1, JNK2α1, JNK2β1 and JNK3α1, which represent the p46 isoforms, and JNK1α2, JNK1β2, JNK2α2, JNK2β2 and JNK3β2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and ransformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38.
Concentration: 1 mg/mL
Immunogen: Synthesized peptide derived from human JNK1/2/3 around the non-phosphorylation site of Thr183.
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification method: Affinity purification
Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000
Calculated MW: 48kDa
ObservedMW: 44kDa
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JNK1/2/3 Polyclonal Antibody
JNK1/2/3 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: JNK1/2/3
Target Synonym: MAPK8;JNK1;PRKM8;SAPK1;SAPK1C;Mitogen-activated protein kinase 8;MAP kinase 8;MAPK 8;JNK-46;Stress-activated protein kinase 1c;SAPK1c;Stress-activated protein kinase JNK1;c-Jun N-terminal kinase 1;MAPK9;JNK2;PRKM9;SAPK1A;Mi
Research Areas: Cancer;Immunology;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat;Chicken
Application: WB;IHC-p;IF
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P45983,P45984,P53779
Accession:
Background: c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1α1,JNK1β1, JNK2α1, JNK2β1 and JNK3α1, which represent the p46 isoforms, and JNK1α2, JNK1β2, JNK2α2, JNK2β2 and JNK3β2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and ransformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38.
Concentration: 1 mg/mL
Immunogen: Synthesized peptide derived from human JNK1/2/3 around the non-phosphorylation site of Thr183.
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification method: Affinity purification
Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000
Calculated MW: 48kDa
ObservedMW: 44kDa
Original: $62,461.47
-70%$62,461.47
$18,738.44Product Information
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Description
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: JNK1/2/3
Target Synonym: MAPK8;JNK1;PRKM8;SAPK1;SAPK1C;Mitogen-activated protein kinase 8;MAP kinase 8;MAPK 8;JNK-46;Stress-activated protein kinase 1c;SAPK1c;Stress-activated protein kinase JNK1;c-Jun N-terminal kinase 1;MAPK9;JNK2;PRKM9;SAPK1A;Mi
Research Areas: Cancer;Immunology;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat;Chicken
Application: WB;IHC-p;IF
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P45983,P45984,P53779
Accession:
Background: c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1α1,JNK1β1, JNK2α1, JNK2β1 and JNK3α1, which represent the p46 isoforms, and JNK1α2, JNK1β2, JNK2α2, JNK2β2 and JNK3β2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and ransformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38.
Concentration: 1 mg/mL
Immunogen: Synthesized peptide derived from human JNK1/2/3 around the non-phosphorylation site of Thr183.
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification method: Affinity purification
Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000
Calculated MW: 48kDa
ObservedMW: 44kDa
