Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: IMPDH2

Target Synonym: IMDH2;IMP (inosine monophosphate) dehydrogenase 2;IMP dehydrogenase 2;IMP oxireductase 2;IMPD 2;IMPD2;IMPDH 2;IMPDH II;IMPDH-II;Impdh2;Inosine 5' monophosphate dehydrogenase 2;Inosine 5' phosphate dehydrogenase 2;Inosine monophosphate dehydrogenase type II;Inosine-5''-monophosphate dehydrogenase 2

Research Areas: Cancer;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P12268

Accession:

Background: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Concentration: 0.5 mg/mL

Immunogen: Recombinant protein of human IMPDH2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 56kDa

ObservedMW: