GNAS Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: GNAS
Target Synonym: AHO;GSA;GSP;POH;GPSA;NESP;GNAS1;PHP1A;PHP1B;PHP1C;C20orf45
Research Areas: Cancer;Metabolism;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P63092
Accession:
Background: This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses.
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human GNAS
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: WB 1:200-1:1000;IHC 1:25-1:100
Calculated MW: 46kDa
ObservedMW:
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GNAS Polyclonal Antibody
GNAS Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: GNAS
Target Synonym: AHO;GSA;GSP;POH;GPSA;NESP;GNAS1;PHP1A;PHP1B;PHP1C;C20orf45
Research Areas: Cancer;Metabolism;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P63092
Accession:
Background: This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses.
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human GNAS
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: WB 1:200-1:1000;IHC 1:25-1:100
Calculated MW: 46kDa
ObservedMW:
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Description
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: GNAS
Target Synonym: AHO;GSA;GSP;POH;GPSA;NESP;GNAS1;PHP1A;PHP1B;PHP1C;C20orf45
Research Areas: Cancer;Metabolism;Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P63092
Accession:
Background: This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses.
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human GNAS
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: WB 1:200-1:1000;IHC 1:25-1:100
Calculated MW: 46kDa
ObservedMW:
