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GCK Polyclonal Antibody

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GCK Polyclonal Antibody

GCK Polyclonal Antibody

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: GCK

Target Synonym: ATP:D-hexose 6-phosphotransferase;FGQTL3;GCK;GK;GLK;Glucokinase;Hexokinase D pancreatic isozyme;Hexokinase type IV;Hexokinase-4;Hexokinase-D;HHF3;HK IV;HK4;HKIV;HXK4;HXKP;LGLK;MODY2

Research Areas: Cancer;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P52792

Accession:

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Concentration: 1 mg/mL

Immunogen: Recombinant Mouse Glucokinase protein

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:1000-1:2000;IHC 1:100-1:200;IF 1:100-1:400

Calculated MW: 52 kDa

ObservedMW: 52kDa

$234.01
GCK Polyclonal Antibody
$234.01

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Description

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: GCK

Target Synonym: ATP:D-hexose 6-phosphotransferase;FGQTL3;GCK;GK;GLK;Glucokinase;Hexokinase D pancreatic isozyme;Hexokinase type IV;Hexokinase-4;Hexokinase-D;HHF3;HK IV;HK4;HKIV;HXK4;HXKP;LGLK;MODY2

Research Areas: Cancer;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P52792

Accession:

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Concentration: 1 mg/mL

Immunogen: Recombinant Mouse Glucokinase protein

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:1000-1:2000;IHC 1:100-1:200;IF 1:100-1:400

Calculated MW: 52 kDa

ObservedMW: 52kDa