DMTN Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: DMTN
Target Synonym: DEMA;DEMA;Dematin;DMT;EPB49;erythrocyte membrane protein band 4.9 (dematin);Erythrocyte membrane protein band 4.9
Research Areas: Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q08495
Accession:
Background: The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms. DMTN (Dematin Actin Binding Protein) is a Protein Coding gene. Diseases associated with DMTN include Hypotrichosis and Hereditary Spherocytosis. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Miscellaneous transport and binding events. GO annotations related to this gene include receptor binding and protein self-association. An important paralog of this gene is ABLIM1.
Concentration: 1.5 mg/mL
Immunogen: Synthetic peptide of human DMTN
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Dilution: WB 1:500-1:2000;IHC 1:20-1:100
Calculated MW: 46 kDa
ObservedMW: Refer to figures
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DMTN Polyclonal Antibody
DMTN Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: DMTN
Target Synonym: DEMA;DEMA;Dematin;DMT;EPB49;erythrocyte membrane protein band 4.9 (dematin);Erythrocyte membrane protein band 4.9
Research Areas: Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q08495
Accession:
Background: The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms. DMTN (Dematin Actin Binding Protein) is a Protein Coding gene. Diseases associated with DMTN include Hypotrichosis and Hereditary Spherocytosis. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Miscellaneous transport and binding events. GO annotations related to this gene include receptor binding and protein self-association. An important paralog of this gene is ABLIM1.
Concentration: 1.5 mg/mL
Immunogen: Synthetic peptide of human DMTN
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Dilution: WB 1:500-1:2000;IHC 1:20-1:100
Calculated MW: 46 kDa
ObservedMW: Refer to figures
Product Information
Product Information
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Description
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: DMTN
Target Synonym: DEMA;DEMA;Dematin;DMT;EPB49;erythrocyte membrane protein band 4.9 (dematin);Erythrocyte membrane protein band 4.9
Research Areas: Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse
Application: WB;IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q08495
Accession:
Background: The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms. DMTN (Dematin Actin Binding Protein) is a Protein Coding gene. Diseases associated with DMTN include Hypotrichosis and Hereditary Spherocytosis. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Miscellaneous transport and binding events. GO annotations related to this gene include receptor binding and protein self-association. An important paralog of this gene is ABLIM1.
Concentration: 1.5 mg/mL
Immunogen: Synthetic peptide of human DMTN
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Dilution: WB 1:500-1:2000;IHC 1:20-1:100
Calculated MW: 46 kDa
ObservedMW: Refer to figures
