DDIT4 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: DDIT4
Target Synonym: DDIT4;DDIT4;Dig2;DNA damage inducible transcript 4;DNA damage inducible transcript 4 protein;DNA damage-inducible transcript 4 protein;FLJ20500;HIF 1 responsive protein RTP801;HIF 1 responsive RTP801;HIF-1 responsive protein RTP801;Protein regulated in development and DNA damage response 1;REDD-1;REDD1;RTP801
Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q9NX09
Accession:
Background: REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS). REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness.
Concentration: 0.8 mg/mL
Immunogen: Recombinant protein of human DDIT4
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
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DDIT4 Polyclonal Antibody
DDIT4 Polyclonal Antibody
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: DDIT4
Target Synonym: DDIT4;DDIT4;Dig2;DNA damage inducible transcript 4;DNA damage inducible transcript 4 protein;DNA damage-inducible transcript 4 protein;FLJ20500;HIF 1 responsive protein RTP801;HIF 1 responsive RTP801;HIF-1 responsive protein RTP801;Protein regulated in development and DNA damage response 1;REDD-1;REDD1;RTP801
Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q9NX09
Accession:
Background: REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS). REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness.
Concentration: 0.8 mg/mL
Immunogen: Recombinant protein of human DDIT4
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: DDIT4
Target Synonym: DDIT4;DDIT4;Dig2;DNA damage inducible transcript 4;DNA damage inducible transcript 4 protein;DNA damage-inducible transcript 4 protein;FLJ20500;HIF 1 responsive protein RTP801;HIF 1 responsive RTP801;HIF-1 responsive protein RTP801;Protein regulated in development and DNA damage response 1;REDD-1;REDD1;RTP801
Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q9NX09
Accession:
Background: REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS). REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness.
Concentration: 0.8 mg/mL
Immunogen: Recombinant protein of human DDIT4
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
