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CYP2E1 Polyclonal Antibody

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CYP2E1 Polyclonal Antibody

CYP2E1 Polyclonal Antibody

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CYP2E1

Target Synonym: 4-nitrophenol 2-hydroxylase;CP2E1;CPE1;CYP2E;Cyp2e1;CYPIIE1;Cytochrome P450 2E1;Cytochrome P450 isozyme 3A;Cytochrome P450 LM3A;Cytochrome P450;family 2;subfamily e;polypeptide 1;cytochrome P450;subfamily IIE (ethanol-inducible);polypeptide 1;Cytochrome P450;subfamily IIE;Cytochrome P450-ALC;Cytochrome P450-J;Cytochrome P450RLM6;EC 1.14.13.-;EC 1.14.13.n7;Ethanol-inducible P450;Flavoprotein-linked monooxygenase;MGC133529;Microsomal monooxygenase;OTTHUMP00000020813;OTTHUMP00000046571;P450 ALC;P450-J;P450C2E;P450J;P450RLM6;Xenobiotic monooxygenase

Research Areas: Cancer;Cardiovascular;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P05181

Accession:

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Concentration: 0.5 mg/mL

Immunogen: Recombinant protein of human CYP2E1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 57kDa

ObservedMW:

$2,101,444.36

Original: $7,004,814.54

-70%
CYP2E1 Polyclonal Antibody

$7,004,814.54

$2,101,444.36

Product Information

Shipping & Returns

Description

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CYP2E1

Target Synonym: 4-nitrophenol 2-hydroxylase;CP2E1;CPE1;CYP2E;Cyp2e1;CYPIIE1;Cytochrome P450 2E1;Cytochrome P450 isozyme 3A;Cytochrome P450 LM3A;Cytochrome P450;family 2;subfamily e;polypeptide 1;cytochrome P450;subfamily IIE (ethanol-inducible);polypeptide 1;Cytochrome P450;subfamily IIE;Cytochrome P450-ALC;Cytochrome P450-J;Cytochrome P450RLM6;EC 1.14.13.-;EC 1.14.13.n7;Ethanol-inducible P450;Flavoprotein-linked monooxygenase;MGC133529;Microsomal monooxygenase;OTTHUMP00000020813;OTTHUMP00000046571;P450 ALC;P450-J;P450C2E;P450J;P450RLM6;Xenobiotic monooxygenase

Research Areas: Cancer;Cardiovascular;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P05181

Accession:

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Concentration: 0.5 mg/mL

Immunogen: Recombinant protein of human CYP2E1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 57kDa

ObservedMW:

CYP2E1 Polyclonal Antibody | GeneBio