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CHRNA7 Polyclonal Antibody

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CHRNA7 Polyclonal Antibody

CHRNA7 Polyclonal Antibody

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CHRFAM7A

Target Synonym: 7nAChR;a7 nicotinic acetylcholine receptor;acetylcholine receptor;neuronal nicotinic;alpha-7 subunit;ACHA7;AChR;Acra7;alpha 7 neuronal nicotinic acetylcholine receptor;alpha-7 nicotinic cholinergic receptor subunit;alpha7;cholinergic receptor;neuronal nicotinic;alpha polypeptide 7;cholinergic receptor;nicotinic;alpha 7 (neuronal);cholinergic receptor;nicotinic;alpha 7;cholinergic receptor;nicotinic;alpha polypeptide 7;CHRNA7;CHRNA7-2;NACHRA7;neuronal acetylcholine receptor protein;alpha-7 chain;Neuronal acetylcholine receptor subunit alpha-7

Research Areas: Cancer;Metabolism;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P36544

Accession:

Background: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human CHRFAM7A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 46kDa

ObservedMW:

$358.65
CHRNA7 Polyclonal Antibody
$358.65

Product Information

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Description

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CHRFAM7A

Target Synonym: 7nAChR;a7 nicotinic acetylcholine receptor;acetylcholine receptor;neuronal nicotinic;alpha-7 subunit;ACHA7;AChR;Acra7;alpha 7 neuronal nicotinic acetylcholine receptor;alpha-7 nicotinic cholinergic receptor subunit;alpha7;cholinergic receptor;neuronal nicotinic;alpha polypeptide 7;cholinergic receptor;nicotinic;alpha 7 (neuronal);cholinergic receptor;nicotinic;alpha 7;cholinergic receptor;nicotinic;alpha polypeptide 7;CHRNA7;CHRNA7-2;NACHRA7;neuronal acetylcholine receptor protein;alpha-7 chain;Neuronal acetylcholine receptor subunit alpha-7

Research Areas: Cancer;Metabolism;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P36544

Accession:

Background: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human CHRFAM7A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 46kDa

ObservedMW: