Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ACOD1

Target Synonym: ACOD1;Aconitate decarboxylase 1;Aconitate decarboxylase;CAD;Cis aconitate decarboxylase;Immune responsive gene 1 protein homolog;Immune-responsive gene 1 protein homolog;Immunoresponsive 1 homolog (mouse);Irg1;IRG1;OC116;OPTB1;TCTIRC7

Research Areas: Metabolism;Immunology;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: A6NK06

Accession:

Background: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

Concentration: 1.32 mg/mL

Immunogen: Synthetic peptide of human ACOD1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 53 kDa

ObservedMW: Refer to figures