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ABCA4 Polyclonal Antibody

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ABCA4 Polyclonal Antibody

ABCA4 Polyclonal Antibody

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ABCA4

Target Synonym: ABC 10;ABC A4;ABC transporter;retinal-specific;ABC10;ABCA 4;abcA4;ABCA4;ABCR;ARMD 2;ARMD2;ATP binding cassette 10;ATP binding cassette sub family A member 4;ATP binding cassette sub family A member4;ATP binding cassette transporter;ATP binding cassette transporter retinal specific;ATP binding cassette;sub family A (ABC1);member 4;ATP binding cassette;sub family A (ABC1);member4;ATP binding cassette10;ATP binding transporter;retina specific;ATP-binding cassette sub-family A member 4;CORD 3;CORD3;DKFZp781N1972;FFM;FLJ17534;Photoreceptor rim protein;Retina specific ABC transporter;Retinal specific ATP binding cassette transporter;Retinal-specific ATP-binding cassette transporter;RIM ABC transporter;RIM protein;RmP;RP 19;RP19;Stargardt disease protein;STGD;STGD1

Research Areas: Cancer;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P78363

Accession:

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Concentration: 0.2 mg/mL

Immunogen: Synthetic peptide of human ABCA4

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:25-1:100

Calculated MW:

ObservedMW:

$460.42

Original: $1,534.73

-70%
ABCA4 Polyclonal Antibody

$1,534.73

$460.42

Product Information

Shipping & Returns

Description

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ABCA4

Target Synonym: ABC 10;ABC A4;ABC transporter;retinal-specific;ABC10;ABCA 4;abcA4;ABCA4;ABCR;ARMD 2;ARMD2;ATP binding cassette 10;ATP binding cassette sub family A member 4;ATP binding cassette sub family A member4;ATP binding cassette transporter;ATP binding cassette transporter retinal specific;ATP binding cassette;sub family A (ABC1);member 4;ATP binding cassette;sub family A (ABC1);member4;ATP binding cassette10;ATP binding transporter;retina specific;ATP-binding cassette sub-family A member 4;CORD 3;CORD3;DKFZp781N1972;FFM;FLJ17534;Photoreceptor rim protein;Retina specific ABC transporter;Retinal specific ATP binding cassette transporter;Retinal-specific ATP-binding cassette transporter;RIM ABC transporter;RIM protein;RmP;RP 19;RP19;Stargardt disease protein;STGD;STGD1

Research Areas: Cancer;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P78363

Accession:

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Concentration: 0.2 mg/mL

Immunogen: Synthetic peptide of human ABCA4

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:25-1:100

Calculated MW:

ObservedMW: